Head of Protein Engineering

hace 2 días


Cuernavaca, México Loïacono Executive Search A tiempo completo

Head of Protein Engineering - Biotech - Cuernavaca Cuernavaca (Mexico) or Munich (Germany) - Full time Company Our client is an early-stage biotechnology product company developing a proprietary smart nano-delivery platform based on protein-engineered nanocapsules. The technology enables on-demand release of active compounds through protein-based sensing mechanisms, significantly reducing chemical usage, cost and environmental impact. While the first commercial application is focused on high-value agriculture, the core technology is deeply rooted in pharma-like molecular design, with strong potential applications in pharmaceuticals, nutraceuticals, cosmetics and life sciences. The company operates across Mexico, Argentina and Europe, is running advanced pilot programs, and is preparing for its next institutional funding round. Mission Own and lead the protein engineering strategy, with a strong focus on antibody-based and antibody-like systems. Design, develop and optimize protein sensors whose mechanism of action is analogous to antibody–antigen interactions. Lead the molecular design and validation of sensing proteins responsible for the smart release mechanism of the nanocapsules. Translate bioinformatic and structural protein data into experimentally validated protein constructs. Define and execute high-throughput screening strategies to test large numbers of protein variants in parallel. Ensure scientific robustness of binding specificity, affinity, selectivity and stability of engineered proteins. Lead and mentor a multidisciplinary scientific team (bioinformatics, microbiology, chemistry, process development). Structure scientific roadmaps aligned with product development, scale-up and investor milestones. Act as the scientific authority for protein-based sensing mechanisms internally and externally. Balance deep scientific rigor with startup execution, speed, cost awareness and scalability constraints. Your Profile PhD or equivalent experience in Protein Engineering, Biotechnology, Bioengineering, Bioinformatics or related fields. Mandatory and extensive hands-on experience with antibodies or antibody-like systems. Proven background in antibody engineering, antibody design, binding assays or immune-inspired sensing mechanisms. Strong understanding of protein–protein interactions, structure–function relationships and molecular recognition. Experience working with high-throughput screening platforms for protein variants. Previous exposure to pharma, biotech, or biologics-driven environments is highly preferred. Demonstrated ability to lead scientific teams and define complex R&D strategies. Ability to operate in an early-stage startup, combining scientific excellence with pragmatism. Strong communication skills and capacity to interface with investors and non-scientific stakeholders. Fluent English is mandatory. Willingness to work on-site in Cuernavaca (Mexico) or Munich (Germany). Benefits Full-time senior leadership role. High-impact position critical to technology validation, scalability and fundraising success. Location: Cuernavaca (Mexico) or Munich (Germany), aligned with laboratory capabilities (high-throughput systems). Competitive compensation aligned with senior biotech profiles and company stage. Significant scientific ownership and long-term growth potential within the company. #J-18808-Ljbffr



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